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Construction and expression of a human/mouse chimeric CD19 monoclonal antibody: Successful modification of a murine IgM to a chimeric IgG

CD19 is a specific surface marker of B cells. A murine IgM-subtype antibody, 2E8, was generated previously and assigned to the CD19 category by the 6th International Workshop and Conference on Human Leukocyte Differentiation Antigens in 1996. In the present study, the 2E8 Fv gene was inserted into a...

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Bibliographic Details
Main Authors: XU, WEIQUN, ZHANG, LINGYAN, ZHANG, YI, TANG, YONGMIN
Format: Artigo
Language:Inglês
Published: D.A. Spandidos 2014
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3961107/
https://ncbi.nlm.nih.gov/pubmed/24669239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/etm.2014.1511
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