A Nonhuman Primate Model for the Selective Elimination of CD8+ Lymphocytes Using a Mouse-Human Chimeric Monoclonal Antibody

Nonhuman primates provide valuable animal models for human diseases. However, studies assessing the role of cell-mediated immune responses have been difficult to perform in nonhuman primates. We have shown that CD8+ lymphocyte-mediated immunity in rhesus monkeys can be selectively eliminated using t...

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Detalhes bibliográficos
Main Authors: Schmitz, Jörn E., Simon, Meredith A., Kuroda, Marcelo J., Lifton, Michelle A., Ollert, Markus W., Vogel, Carl-Wilhelm, Racz, Paul, Tenner-Racz, Klara, Scallon, Bernard J., Dalesandro, Margaret, Ghrayeb, John, Rieber, E. Peter, Sasseville, Vito G., Reimann, Keith A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 1999
Assuntos:
Animal Model
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1866630/
https://ncbi.nlm.nih.gov/pubmed/10362819
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