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Biochemical Signaling of PD-1 on T Cells and Its Functional Implications

Maintenance of peripheral tolerance is essential for homeostasis of the immune system. While central tolerance mechanisms result in deletion of the majority of self-reactive T cells, T lymphocytes specific for self-antigens also escape this process and circulate in the periphery. To control the deve...

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Detalhes bibliográficos
Main Authors: Boussiotis, Vassiliki A., Chatterjee, Pranam, Li, Lequn
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4151049/
https://ncbi.nlm.nih.gov/pubmed/25098287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/PPO.0000000000000059
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