טוען...
Rap1A regulates generation of T regulatory cells via LFA-1-dependent and LFA-1-independent mechanisms
The small GTPase Rap1A has a critical role in regulating cell-matrix and cell-cell adhesion. In T lymphocytes, Rap1A mediates LFA-1 activation and LFA-1-mediated adhesion. LFA-1 reduces the threshold of TCR signals for low affinity ligands. Previously, we determined that mice expressing constitutive...
שמור ב:
| Main Authors: | , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
2010
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2966523/ https://ncbi.nlm.nih.gov/pubmed/20864093 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellimm.2010.08.014 |
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