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Specific integrin α and β chain phosphorylations regulate LFA-1 activation through affinity-dependent and -independent mechanisms

Integrins are adhesion receptors that are crucial to the functions of multicellular organisms. Integrin-mediated adhesion is a complex process that involves both affinity regulation and cytoskeletal coupling, but the molecular mechanisms behind this process have remained incompletely understood. In...

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Hlavní autoři: Fagerholm, Susanna C., Hilden, Tiina J., Nurmi, Susanna M., Gahmberg, Carl G.
Médium: Artigo
Jazyk:Inglês
Vydáno: The Rockefeller University Press 2005
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2171568/
https://ncbi.nlm.nih.gov/pubmed/16301335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200504016
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