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Increased extracellular pressure enhances cancer cell integrin-binding affinity through phosphorylation of β(1)-integrin at threonine 788/789
Increased extracellular pressure stimulates β(1)-integrin-dependent cancer cell adhesion. We asked whether pressure-induced adhesion is mediated by changes in β(1)-integrin binding affinity or avidity and whether these changes are phosphorylation dependent. We evaluated integrin affinity and cluster...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Physiological Society
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2637001/ https://ncbi.nlm.nih.gov/pubmed/19005162 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00355.2008 |
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