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Identification of Integrin β Subunit Mutations That Alter Affinity for Extracellular Matrix Ligand
We examined over 50 mutations in the Drosophila βPS integrin subunit that alter integrin function in situ for their ability to bind a soluble monovalent ligand, TWOW-1. Surprisingly, very few of the mutations, which were selected for conditional lethality in the fly, reduce the ligand binding abilit...
Wedi'i Gadw mewn:
| Prif Awduron: | , , , |
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| Fformat: | Artigo |
| Iaith: | Inglês |
| Cyhoeddwyd: |
American Society for Biochemistry and Molecular Biology
2011
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| Pynciau: | |
| Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3162457/ https://ncbi.nlm.nih.gov/pubmed/21757698 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.254797 |
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