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Identification of Integrin β Subunit Mutations that Alter Heterodimer Function In Situ

We conducted a genetic screen for mutations in myospheroid, the gene encoding the Drosophila βPS integrin subunit, and identified point mutants in all of the structural domains of the protein. Surprisingly, we find that mutations in very strongly conserved residues will often allow sufficient integr...

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Detalhes bibliográficos
Main Authors: Jannuzi, Alison L., Bunch, Thomas A., West, Robert F., Brower, Danny L.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC491840/
https://ncbi.nlm.nih.gov/pubmed/15194810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E04-02-0085
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