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Identification of Integrin β Subunit Mutations that Alter Heterodimer Function In Situ
We conducted a genetic screen for mutations in myospheroid, the gene encoding the Drosophila βPS integrin subunit, and identified point mutants in all of the structural domains of the protein. Surprisingly, we find that mutations in very strongly conserved residues will often allow sufficient integr...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , , , |
|---|---|
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
The American Society for Cell Biology
2004
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC491840/ https://ncbi.nlm.nih.gov/pubmed/15194810 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E04-02-0085 |
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