Regulation of LFA-1–dependent inflammatory cell recruitment by Cbl-b and 14-3-3 proteins

Inside-out signaling regulation of the β2-integrin leukocyte function–associated antigen-1 (LFA-1) by different cytoplasmic proteins, including 14-3-3 proteins, is essential for adhesion and migration of immune cells. Here, we identify a new pathway for the regulation of LFA-1 activity by Cbl-b, an...

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Autores principales: Choi, Eun Young, Orlova, Valeria V., Fagerholm, Susanna C., Nurmi, Susanna M., Zhang, Li, Ballantyne, Christie M., Gahmberg, Carl G., Chavakis, Triantafyllos
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society of Hematology 2008
Materias:
Immunobiology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2275024/
https://ncbi.nlm.nih.gov/pubmed/18239087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2007-07-103077
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