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A novel pathway of HMGB1-mediated inflammatory cell recruitment that requires Mac-1-integrin
High-mobility group box 1 (HMGB1) is released extracellularly upon cell necrosis acting as a mediator in tissue injury and inflammation. However, the molecular mechanisms for the proinflammatory effect of HMGB1 are poorly understood. Here, we define a novel function of HMGB1 in promoting Mac-1-depen...
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| Главные авторы: | , , , , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Nature Publishing Group
2007
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1852832/ https://ncbi.nlm.nih.gov/pubmed/17268551 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601552 |
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