The Pattern Recognition Receptor (RAGE) Is a Counterreceptor for Leukocyte Integrins: A Novel Pathway for Inflammatory Cell Recruitment

The pattern recognition receptor, RAGE (receptor for advanced glycation endproducts), propagates cellular dysfunction in several inflammatory disorders and diabetes. Here we show that RAGE functions as an endothelial adhesion receptor promoting leukocyte recruitment. In an animal model of thioglycol...

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Hauptverfasser: Chavakis, Triantafyllos, Bierhaus, Angelika, Al-Fakhri, Nadia, Schneider, Darius, Witte, Steffen, Linn, Thomas, Nagashima, Mariko, Morser, John, Arnold, Bernd, Preissner, Klaus T., Nawroth, Peter P.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Rockefeller University Press 2003
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2194124/
https://ncbi.nlm.nih.gov/pubmed/14623906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20030800
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