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Biochemical Signaling of PD-1 on T Cells and Its Functional Implications
Maintenance of peripheral tolerance is essential for homeostasis of the immune system. While central tolerance mechanisms result in deletion of the majority of self-reactive T cells, T lymphocytes specific for self-antigens also escape this process and circulate in the periphery. To control the deve...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2014
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4151049/ https://ncbi.nlm.nih.gov/pubmed/25098287 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/PPO.0000000000000059 |
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