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Chimeric bifunctional oligonucleotides as a novel tool to invade telomerase assembly

Telomerase is a key participant in the telomere length maintaining system in eukaryotic cells. Telomerase RNA and protein reverse transcriptase subunits are essential for the appearance of active telomerase in vitro. Telomerase is active in many cancer types and is a potential target for anticancer...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Azhibek, Dulat, Zvereva, Maria, Zatsepin, Timofei, Rubtsova, Maria, Dontsova, Olga
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Oxford University Press 2014
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4150790/
https://ncbi.nlm.nih.gov/pubmed/25081209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku688
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