Structure and function of the N-terminal domain of the yeast telomerase reverse transcriptase

The elongation of single-stranded DNA repeats at the 3′-ends of chromosomes by telomerase is a key process in maintaining genome integrity in eukaryotes. Abnormal activation of telomerase leads to uncontrolled cell division, whereas its down-regulation is attributed to ageing and several pathologies...

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Bibliografische gegevens
Gepubliceerd in:Nucleic Acids Res
Hoofdauteurs: Petrova, Olga A, Mantsyzov, Alexey B, Rodina, Elena V, Efimov, Sergey V, Hackenberg, Claudia, Hakanpää, Johanna, Klochkov, Vladimir V, Lebedev, Andrej A, Chugunova, Anastasia A, Malyavko, Alexander N, Zatsepin, Timofei S, Mishin, Alexey V, Zvereva, Maria I, Lamzin, Victor S, Dontsova, Olga A, Polshakov, Vladimir I
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 2018
Onderwerpen:
Structural Biology
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5814841/
https://ncbi.nlm.nih.gov/pubmed/29294091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx1275
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