The genome-wide transcription response to telomerase deficiency in the thermotolerant yeast Hansenula polymorpha DL-1

BACKGROUND: In the course of replication of eukaryotic chromosomes, the telomere length is maintained due to activity of telomerase, the ribonucleoprotein reverse transcriptase. Abolishing telomerase function causes progressive shortening of telomeres and, ultimately, cell cycle arrest and replicati...

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Veröffentlicht in:BMC Genomics
Hauptverfasser: Beletsky, Alexey V., Malyavko, Alexander N., Sukhanova, Maria V., Mardanova, Eugenia S., Zvereva, Maria I., Petrova, Olga A., Parfenova, Yulia Yu., Rubtsova, Maria P., Mardanov, Andrey V., Lavrik, Olga I., Dontsova, Olga A., Ravin, Nikolai V.
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2017
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5490237/
https://ncbi.nlm.nih.gov/pubmed/28659185
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-017-3889-x
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