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PARP1 Regulates the Biogenesis and Activity of Telomerase Complex Through Modification of H/ACA-Proteins

Poly(ADP-ribose) polymerase 1 (PARP1) is established as a key regulator of the cellular DNA damage response and apoptosis. In addition, PARP1 participates in the global regulation of DNA repair, transcription, telomere maintenance, and inflammation response by modulating various DNA-protein and prot...

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書目詳細資料
發表在:Front Cell Dev Biol
Main Authors: Savelyev, Nikita V., Shepelev, Nikita M., Lavrik, Olga I., Rubtsova, Maria P., Dontsova, Olga A.
格式: Artigo
語言:Inglês
出版: Frontiers Media S.A. 2021
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC8170401/
https://ncbi.nlm.nih.gov/pubmed/34095104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2021.621134
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