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An Enhanced H/ACA RNP Assembly Mechanism for Human Telomerase RNA

The integral telomerase RNA subunit templates the synthesis of telomeric repeats. The biological accumulation of human telomerase RNA (hTR) requires hTR H/ACA domain assembly with the same proteins that assemble on other human H/ACA RNAs. Despite this shared RNP composition, hTR accumulation is part...

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Bibliographic Details
Main Authors: Egan, Emily D., Collins, Kathleen
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2012
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3434483/
https://ncbi.nlm.nih.gov/pubmed/22527283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00286-12
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