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An intronic PICALM polymorphism, rs588076, is associated with allelic expression of a PICALM isoform
BACKGROUND: Although genome wide studies have associated single nucleotide polymorphisms (SNP)s near PICALM with Alzheimer’s disease (AD), the mechanism underlying this association is unclear. PICALM is involved in clathrin-mediated endocytosis and modulates Aß clearance in vitro. Comparing allelic...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4150683/ https://ncbi.nlm.nih.gov/pubmed/25169757 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1750-1326-9-32 |
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