CD33 Alzheimer's Risk-Altering Polymorphism, CD33 Expression, and Exon 2 Splicing

Genome-wide association studies are identifying novel Alzheimer's disease (AD) risk factors. Elucidating the mechanism underlying these polymorphisms is critical to the validation process and, by identifying rate-limiting steps in AD risk, may yield novel therapeutic targets. Here, we elucidate...

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Detalhes bibliográficos
Main Authors: Malik, Manasi, Simpson, James F., Parikh, Ishita, Wilfred, Bernard R., Fardo, David W., Nelson, Peter T., Estus, Steven
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2013
Assuntos:
Brief Communications
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3742922/
https://ncbi.nlm.nih.gov/pubmed/23946390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1224-13.2013
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