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Isoform of APOE with retained intron 3; quantitation and identification of an associated single nucleotide polymorphism

BACKGROUND: Alleles of apolipoprotein E (APOE) are the major genetic risk factor for late onset Alzheimer's Disease (LOAD). Recently, an APOE splice variant that retains intron 3 (APOE-I3) was identified. To gain insight into the possible role of this isoform in LOAD, we quantified its expressi...

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Bibliografiske detaljer
Main Authors: Dieter, Laura S, Estus, Steven
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2940878/
https://ncbi.nlm.nih.gov/pubmed/20822524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1750-1326-5-34
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