Oncogenic KRAS signalling in pancreatic cancer

Pancreatic ductal adenocarcinoma (PDAC) is almost universally fatal. The annual number of deaths equals the number of newly diagnosed cases, despite maximal treatment. The overall 5-year survival rate of <5% has remained stubbornly unchanged over the last 30 years, despite tremendous efforts in p...

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Main Authors: Eser, S, Schnieke, A, Schneider, G, Saur, D
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4150259/
https://ncbi.nlm.nih.gov/pubmed/24755884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2014.215
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