Oncogenic KRAS and the EGFR loop in pancreatic carcinogenesis—A connection to licensing nodes

EGFR signaling has a critical role in oncogenic KRAS-driven tumorigenesis of the pancreas, whereas it is dispensable in other organs. The complex signaling network engaged by oncogenic KRAS and its modulation by EGFR signaling, remains incompletely understood. In order to study early signaling event...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Small GTPases
Egile Nagusiak: Schneeweis, Christian, Wirth, Matthias, Saur, Dieter, Reichert, Maximilian, Schneider, Günter
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Taylor & Francis 2017
Gaiak:
Commentary - Commissioned
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6205075/
https://ncbi.nlm.nih.gov/pubmed/27880072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21541248.2016.1262935
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