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Oncogenic KRAS and the EGFR loop in pancreatic carcinogenesis—A connection to licensing nodes

EGFR signaling has a critical role in oncogenic KRAS-driven tumorigenesis of the pancreas, whereas it is dispensable in other organs. The complex signaling network engaged by oncogenic KRAS and its modulation by EGFR signaling, remains incompletely understood. In order to study early signaling event...

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Dettagli Bibliografici
Pubblicato in:Small GTPases
Autori principali: Schneeweis, Christian, Wirth, Matthias, Saur, Dieter, Reichert, Maximilian, Schneider, Günter
Natura: Artigo
Lingua:Inglês
Pubblicazione: Taylor & Francis 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6205075/
https://ncbi.nlm.nih.gov/pubmed/27880072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21541248.2016.1262935
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