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Oncogenic KRAS and the EGFR loop in pancreatic carcinogenesis—A connection to licensing nodes

EGFR signaling has a critical role in oncogenic KRAS-driven tumorigenesis of the pancreas, whereas it is dispensable in other organs. The complex signaling network engaged by oncogenic KRAS and its modulation by EGFR signaling, remains incompletely understood. In order to study early signaling event...

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Détails bibliographiques
Publié dans:Small GTPases
Auteurs principaux: Schneeweis, Christian, Wirth, Matthias, Saur, Dieter, Reichert, Maximilian, Schneider, Günter
Format: Artigo
Langue:Inglês
Publié: Taylor & Francis 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6205075/
https://ncbi.nlm.nih.gov/pubmed/27880072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21541248.2016.1262935
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