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Oncogenic KRAS and the EGFR loop in pancreatic carcinogenesis—A connection to licensing nodes

EGFR signaling has a critical role in oncogenic KRAS-driven tumorigenesis of the pancreas, whereas it is dispensable in other organs. The complex signaling network engaged by oncogenic KRAS and its modulation by EGFR signaling, remains incompletely understood. In order to study early signaling event...

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Detalhes bibliográficos
Publicado no:Small GTPases
Main Authors: Schneeweis, Christian, Wirth, Matthias, Saur, Dieter, Reichert, Maximilian, Schneider, Günter
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6205075/
https://ncbi.nlm.nih.gov/pubmed/27880072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21541248.2016.1262935
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