RAGE is essential for oncogenic KRAS-mediated hypoxic signaling in pancreatic cancer

A hypoxic tumor microenvironment is characteristic of many cancer types, including one of the most lethal, pancreatic cancer. We recently demonstrated that the receptor for advanced glycation end products (RAGE) has an important role in promoting the development of pancreatic cancer and attenuating...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Kang, R, Hou, W, Zhang, Q, Chen, R, Lee, Y J, Bartlett, D L, Lotze, M T, Tang, D, Zeh, H J
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4237264/
https://ncbi.nlm.nih.gov/pubmed/25341034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2014.445
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