RAGE is essential for oncogenic KRAS-mediated hypoxic signaling in pancreatic cancer

A hypoxic tumor microenvironment is characteristic of many cancer types, including one of the most lethal, pancreatic cancer. We recently demonstrated that the receptor for advanced glycation end products (RAGE) has an important role in promoting the development of pancreatic cancer and attenuating...

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Detalles Bibliográficos
Publicado en:Cell Death Dis
Autores principales: Kang, R, Hou, W, Zhang, Q, Chen, R, Lee, Y J, Bartlett, D L, Lotze, M T, Tang, D, Zeh, H J
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 2014
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Original Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4237264/
https://ncbi.nlm.nih.gov/pubmed/25341034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2014.445
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