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Epigenetic landscape during osteoblastogenesis defines a differentiation-dependent Runx2 promoter region
Runx2 is a developmentally regulated gene in vertebrates and is essential for bone formation and skeletal homeostasis. The induction of runx2-P1 isoform transcripts is a hallmark of early osteoblastogenesis. Although previous in vitro studies have defined a minimal Runx2-P1 promoter sequence with we...
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| Main Authors: | , , , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2014
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4149845/ https://ncbi.nlm.nih.gov/pubmed/24881813 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.gene.2014.05.044 |
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