Circulating Tumor Cell Clusters are Oligoclonal Precursors of Breast Cancer Metastasis

Clusters of circulating tumor cells (CTC-clusters) are present in the blood of patients with cancer but their contribution to metastasis is not well defined. Using mouse models with tagged mammary tumors, we demonstrate that CTC-clusters arise from oligoclonal tumor cell groupings and not from intra...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Aceto, Nicola, Bardia, Aditya, Miyamoto, David T., Donaldson, Maria C., Wittner, Ben S., Spencer, Joel A., Yu, Min, Pely, Adam, Engstrom, Amanda, Zhu, Huili, Brannigan, Brian W., Kapur, Ravi, Stott, Shannon L., Shioda, Toshi, Ramaswamy, Sridhar, Ting, David T., Lin, Charles P., Toner, Mehmet, Haber, Daniel A., Maheswaran, Shyamala
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2014
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4149753/
https://ncbi.nlm.nih.gov/pubmed/25171411
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2014.07.013
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