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Isolation of rare recombinants without using selectable markers for one-step seamless BAC mutagenesis

Current laboratory methods to isolate rare (1:10,000 to 1:100,000) bacterial artificial chromosome (BAC) recombinants require selectable markers. Seamless BAC mutagenesis needs two steps: isolation of rare recombinants using selectable markers, followed by marker removal through counterselection. He...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Lyozin, George T., Bressloff, Paul C., Kumar, Amit, Kosaka, Yasuhiro, Demarest, Bradley L., Yost, H. Joseph, Kuehn, Michael R., Brunelli, Luca
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2014
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4149595/
https://ncbi.nlm.nih.gov/pubmed/25028895
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmeth.3030
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