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Improved seamless mutagenesis by recombineering using ccdB for counterselection

Recombineering, which is the use of homologous recombination for DNA engineering in Escherichia coli, usually uses antibiotic selection to identify the intended recombinant. When combined in a second step with counterselection using a small molecule toxin, seamless products can be obtained. Here, we...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Wang, Hailong, Bian, Xiaoying, Xia, Liqiu, Ding, Xuezhi, Müller, Rolf, Zhang, Youming, Fu, Jun, Stewart, A. Francis
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2014
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3950717/
https://ncbi.nlm.nih.gov/pubmed/24369425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt1339
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