Direct cloning and heterologous expression of the salinomycin biosynthetic gene cluster from Streptomyces albus DSM41398 in Streptomyces coelicolor A3(2)

Linear plus linear homologous recombination-mediated recombineering (LLHR) is ideal for obtaining natural product biosynthetic gene clusters from pre-digested bacterial genomic DNA in one or two steps of recombineering. The natural product salinomycin has a potent and selective activity against canc...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Yin, Jia, Hoffmann, Michael, Bian, Xiaoying, Tu, Qiang, Yan, Fu, Xia, Liqiu, Ding, Xuezhi, Francis Stewart, A., Müller, Rolf, Fu, Jun, Zhang, Youming
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2015
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4602208/
https://ncbi.nlm.nih.gov/pubmed/26459865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep15081
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires