Neural stem cell-mediated CE/CPT-11 enzyme/prodrug therapy in transgenic mouse model of intracerebellar medulloblastoma

Medulloblastoma is a heterogeneous diffuse neoplasm that can be highly disseminated, and is the most common malignant childhood brain tumor. Although multimodal treatments have improved survival rates for patients with medulloblastoma, these tumors are associated with high morbidity and mortality. N...

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Detalhes bibliográficos
Main Authors: Gutova, Margarita, Shackleford, Gregory M., Khankaldyyan, Vazgen, Herrmann, Kelsey A., Shi, Xiang-He, Mittelholtz, Kimberly, Abramyants, Yelena, Blanchard, M. Suzette, Kim, Seung U., Annala, Alexander J., Najbauer, Joseph, Synold, Timothy W., D'Apuzzo, Massimo, Barish, Michael E., Moats, Rex A., Aboody, Karen S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4149468/
https://ncbi.nlm.nih.gov/pubmed/22402322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/gt.2012.12
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