Neural Stem Cell-Mediated Enzyme-Prodrug Therapy for Glioma: Preclinical Studies

High-grade gliomas are extremely difficult to treat because they are invasive and therefore are not curable by surgical resection; the toxicity of currently chemo- and radiation therapies limits the doses that can be used. Neural stem cells (NSCs) have inherent tumor-tropic properties that enable th...

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Huvudupphovsmän: Aboody, Karen S., Najbauer, Joseph, Metz, Marianne Z., D’Apuzzo, Massimo, Gutova, Margarita, Annala, Alexander J., Synold, Timothy W., Couture, Larry A., Blanchard, Suzette, Moats, Rex A., Garcia, Elizabeth, Aramburo, Soraya, Valenzuela, Valerie V., Frank, Richard T., Barish, Michael E., Brown, Christine E., Kim, Seung U., Badie, Behnam, Portnow, Jana
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2013
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3864887/
https://ncbi.nlm.nih.gov/pubmed/23658244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.3005365
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