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Global Genetic Determinants of Mitochondrial DNA Copy Number

Many human diseases including development of cancer is associated with depletion of mitochondrial DNA (mtDNA) content. These diseases are collectively described as mitochondrial DNA depletion syndrome (MDS). High similarity between yeast and human mitochondria allows genomic study of the budding yea...

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Autors principals: Zhang, Hengshan, Singh, Keshav K.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4149433/
https://ncbi.nlm.nih.gov/pubmed/25170845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0105242
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