Epigenomic comparison reveals activation of ‘seed’ enhancers during transition from naive to primed pluripotency

Naïve mouse embryonic stem cells (mESCs) and primed epiblast stem cells (mEpiSCs) represent successive snapshots of pluripotency during embryogenesis. Using transcriptomic and epigenomic mapping we show that a small fraction of transcripts are differentially expressed between mESCs and mEpiSCs and t...

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Detalhes bibliográficos
Main Authors: Factor, Daniel C., Corradin, Olivia, Zentner, Gabriel E., Saiakhova, Alina, Song, Lingyun, Chenoweth, Josh G., McKay, Ronald D., Crawford, Gregory E., Scacheri, Peter C., Tesar, Paul J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4149284/
https://ncbi.nlm.nih.gov/pubmed/24905169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2014.05.005
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