The Specific Monomer/Dimer Equilibrium of the Corticotropin-releasing Factor Receptor Type 1 Is Established in the Endoplasmic Reticulum

G protein-coupled receptors (GPCRs) represent the most important drug targets. Although the smallest functional unit of a GPCR is a monomer, it became clear in the past decades that the vast majority of the receptors form dimers. Only very recently, however, data were presented that some receptors m...

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Main Authors: Teichmann, Anke, Gibert, Arthur, Lampe, André, Grzesik, Paul, Rutz, Claudia, Furkert, Jens, Schmoranzer, Jan, Krause, Gerd, Wiesner, Burkhard, Schülein, Ralf
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Signal Transduction
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4148855/
https://ncbi.nlm.nih.gov/pubmed/24966326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.553644
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