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Quinine and Chloroquine Differentially Perturb Heme Monomer–Dimer Equilibrium

Nuclear magnetic resonance (NMR) measurements of magnetic susceptibility have been utilized to study the equilibrium between two forms (high-spin monomer vs the antiferromagnetically coupled μ-oxo dimer) of ferriprotoporphyrin(IX) as a function of pH. The pH dependence of this equilibrium is signifi...

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Detalhes bibliográficos
Main Authors: Casabianca, Leah B., An, David, Natarajan, Jayakumar K., Alumasa, John N., Roepe, Paul D., Wolf, Christian, de Dios, Angel C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2584347/
https://ncbi.nlm.nih.gov/pubmed/18533646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ic800440d
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