Artesunate Activation by Heme in an Aqueous Medium

Por Heller, Laura, Roepe, Paul D., de Dios, Angel C.
Publicado no Inorganica Chim Acta (2019)

Relative to Quinine and Quinidine, Their 9-Epimers Exhibit Decreased Cytostatic Activity and Altered Heme Binding but Similar Cytocidal Activity versus Plasmodium falciparum

Por Gorka, Alexander P., Sherlach, Katy S., de Dios, Angel C., Roepe, Paul D.
Publicado em 2013

The Hydroxyl Functionality and a Rigid Proximal N are Required for Forming a Novel Non-Covalent Quinine-Heme Complex

Por Alumasa, John N., Gorka, Alexander P., Casabianca, Leah B., Comstock, Erica, de Dios, Angel C., Roepe, Paul D.
Publicado em 2010

Quinine and Chloroquine Differentially Perturb Heme Monomer–Dimer Equilibrium

Por Casabianca, Leah B., An, David, Natarajan, Jayakumar K., Alumasa, John N., Roepe, Paul D., Wolf, Christian, de Dios, Angel C.
Publicado em 2008

Overcoming Drug Resistance to Heme-Targeted Antimalarials by Systematic Side Chain Variation of 7-Chloro-4-aminoquinolines

Por Yearick, Kim, Ekoue-Kovi, Kekeli, Iwaniuk, D., Natarajan, Jayakumar K., Alumasa, John, de Dios, Angel C., Roepe, Paul D., Wolf, Christian
Publicado em 2008

Antimalarial Drugs and Heme in Detergent Micelles: An NMR Study

Por Casabianca, Leah B., Kallgren, Joye B., Natarajan, Jayakumar K., Alumasa, John N., Roepe, Paul D., Wolf, Christian, de Dios, Angel C.
Publicado em 2009

Synthesis and antimalarial activity of new 4-amino-7-chloroquinolyl amides, sulfonamides, ureas and thioureas

Por Ekoue-Kovi, Kekeli, Yearick, Kimberly, Iwaniuk, Daniel P., Natarajan, Jayakumar K., Alumasa, John, de Dios, Angel C., Roepe, Paul D., Wolf, Christian
Publicado em 2008

Synthesis and antimalarial activity of new chloroquine analogues carrying a multifunctional linear side chain

Por Iwaniuk, Daniel P., Whetmore, Eric D., Rosa, Nicholas, Ekoue-Kovi, Kekeli, Alumasa, John, de Dios, Angel C., Roepe, Paul D., Wolf, Christian
Publicado em 2009

4-N, 4-S & 4-O Chloroquine Analogues: Influence of Side Chain Length and Quinolyl Nitrogen pKa on Activity vs. Chloroquine Resistant Malaria,

Por Natarajan, Jayakumar K., Alumasa, John, Yearick, Kimberly, Ekoue-Kovi, Kekeli A., Casabianca, Leah B., de Dios, Angel C., Wolf, Christian, Roepe, Paul D.
Publicado em 2008

Cytostatic versus Cytocidal Activities of Chloroquine Analogues and Inhibition of Hemozoin Crystal Growth

Por Gorka, Alexander P., Alumasa, John N., Sherlach, Katy S., Jacobs, Lauren M., Nickley, Katherine B., Brower, Jonathan P., de Dios, Angel C., Roepe, Paul D.
Publicado em 2013