Synthesis and antimalarial activity of new 4-amino-7-chloroquinolyl amides, sulfonamides, ureas and thioureas

We report the synthesis and in vitro antimalarial activities of more than 50 7-chloro-4-aminoquinolyl-derived sulfonamides 3-8 and 11-26, ureas 19-22, thioureas 23-26, and amides 27-54. Many of the CQ analogues prepared for this study showed submicromolar antimalarial activity versus HB3 (chloroquin...

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Detaylı Bibliyografya
Asıl Yazarlar: Ekoue-Kovi, Kekeli, Yearick, Kimberly, Iwaniuk, Daniel P., Natarajan, Jayakumar K., Alumasa, John, de Dios, Angel C., Roepe, Paul D., Wolf, Christian
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2008
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Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2647815/
https://ncbi.nlm.nih.gov/pubmed/19041248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2008.11.009
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