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Constitutive Gα(i) Coupling Activity of Very Large G Protein-coupled Receptor 1 (VLGR1) and Its Regulation by PDZD7 Protein

The very large G protein-coupled receptor 1 (VLGR1) is a core component in inner ear hair cell development. Mutations in the vlgr1 gene cause Usher syndrome, the symptoms of which include congenital hearing loss and progressive retinitis pigmentosa. However, the mechanism of VLGR1-regulated intracel...

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Bibliographic Details
Main Authors: Hu, Qiao-Xia, Dong, Jun-Hong, Du, Hai-Bo, Zhang, Dao-Lai, Ren, Hong-Ze, Ma, Ming-Liang, Cai, Yuan, Zhao, Tong-Chao, Yin, Xiao-Lei, Yu, Xiao, Xue, Tian, Xu, Zhi-Gang, Sun, Jin-Peng
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2014
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4148852/
https://ncbi.nlm.nih.gov/pubmed/24962568
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.549816
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