Constitutive Gα(i) Coupling Activity of Very Large G Protein-coupled Receptor 1 (VLGR1) and Its Regulation by PDZD7 Protein

The very large G protein-coupled receptor 1 (VLGR1) is a core component in inner ear hair cell development. Mutations in the vlgr1 gene cause Usher syndrome, the symptoms of which include congenital hearing loss and progressive retinitis pigmentosa. However, the mechanism of VLGR1-regulated intracel...

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Detalhes bibliográficos
Main Authors: Hu, Qiao-Xia, Dong, Jun-Hong, Du, Hai-Bo, Zhang, Dao-Lai, Ren, Hong-Ze, Ma, Ming-Liang, Cai, Yuan, Zhao, Tong-Chao, Yin, Xiao-Lei, Yu, Xiao, Xue, Tian, Xu, Zhi-Gang, Sun, Jin-Peng
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Cell Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4148852/
https://ncbi.nlm.nih.gov/pubmed/24962568
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.549816
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