Adult Thymus Contains FoxN1(−) Epithelial Stem Cells that Are Bipotent for Medullary and Cortical Thymic Epithelial Lineages

Within the thymus, two major thymic epithelial cell (TEC) subsets—cortical and medullary TECs—provide unique structural and functional niches for T cell development and establishment of central tolerance. Both lineages are believed to originate from a common progenitor cell, yet the cellular and mol...

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Auteurs principaux: Ucar, Ahmet, Ucar, Olga, Klug, Paula, Matt, Sonja, Brunk, Fabian, Hofmann, Thomas G., Kyewski, Bruno
Format: Artigo
Langue:Inglês
Publié: Cell Press 2014
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4148705/
https://ncbi.nlm.nih.gov/pubmed/25148026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2014.07.005
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