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Adult Thymus Contains FoxN1(−) Epithelial Stem Cells that Are Bipotent for Medullary and Cortical Thymic Epithelial Lineages
Within the thymus, two major thymic epithelial cell (TEC) subsets—cortical and medullary TECs—provide unique structural and functional niches for T cell development and establishment of central tolerance. Both lineages are believed to originate from a common progenitor cell, yet the cellular and mol...
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| Главные авторы: | , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Cell Press
2014
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4148705/ https://ncbi.nlm.nih.gov/pubmed/25148026 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2014.07.005 |
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