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Thymopoiesis in mice depends on a Foxn1-positive thymic epithelial cell lineage
The thymus is essential for T-cell development. Here, we focus on the role of the transcription factor Foxn1 in the development and function of thymic epithelial cells (TECs) of the mouse. TECs are of endodermal origin; they initially express Foxn1 and give rise to orthotopic (thoracic) and addition...
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| Autori principali: | , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
2010
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2944754/ https://ncbi.nlm.nih.gov/pubmed/20823228 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1004623107 |
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