Thymopoiesis in mice depends on a Foxn1-positive thymic epithelial cell lineage

The thymus is essential for T-cell development. Here, we focus on the role of the transcription factor Foxn1 in the development and function of thymic epithelial cells (TECs) of the mouse. TECs are of endodermal origin; they initially express Foxn1 and give rise to orthotopic (thoracic) and addition...

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Detaylı Bibliyografya
Asıl Yazarlar: Corbeaux, Tatiana, Hess, Isabell, Swann, Jeremy B., Kanzler, Benoît, Haas-Assenbaum, Annette, Boehm, Thomas
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2010
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2944754/
https://ncbi.nlm.nih.gov/pubmed/20823228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1004623107
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