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Thymopoiesis in mice depends on a Foxn1-positive thymic epithelial cell lineage

The thymus is essential for T-cell development. Here, we focus on the role of the transcription factor Foxn1 in the development and function of thymic epithelial cells (TECs) of the mouse. TECs are of endodermal origin; they initially express Foxn1 and give rise to orthotopic (thoracic) and addition...

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Autores principales: Corbeaux, Tatiana, Hess, Isabell, Swann, Jeremy B., Kanzler, Benoît, Haas-Assenbaum, Annette, Boehm, Thomas
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2010
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2944754/
https://ncbi.nlm.nih.gov/pubmed/20823228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1004623107
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