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A logrank test-based method for sizing clinical trials with two co-primary time-to-event endpoints

We discuss sample size determination for clinical trials evaluating the joint effects of an intervention on two potentially correlated co-primary time-to-event endpoints. For illustration, we consider the most common case, a comparison of two randomized groups, and use typical copula families to mod...

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Bibliografiset tiedot
Päätekijät: Sugimoto, Tomoyuki, Sozu, Takashi, Hamasaki, Toshimitsu, Evans, Scott R.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Oxford University Press 2013
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4148615/
https://ncbi.nlm.nih.gov/pubmed/23307913
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/biostatistics/kxs057
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