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HIV-1 Expression Within Resting CD4(+) T Cells After Multiple Doses of Vorinostat

Background. A single dose of the histone deacetylase inhibitor vorinostat (VOR) up-regulates HIV RNA expression within resting CD4(+) T cells of treated, aviremic human immunodeficiency virus (HIV)–positive participants. The ability of multiple exposures to VOR to repeatedly disrupt latency has not...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Archin, Nancy M., Bateson, Rosalie, Tripathy, Manoj K., Crooks, Amanda M., Yang, Kuo-Hsiung, Dahl, Noelle P., Kearney, Mary F., Anderson, Elizabeth M., Coffin, John M., Strain, Matthew C., Richman, Douglas D., Robertson, Kevin R., Kashuba, Angela D., Bosch, Ronald J., Hazuda, Daria J., Kuruc, Joann D., Eron, Joseph J., Margolis, David M.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Oxford University Press 2014
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4148603/
https://ncbi.nlm.nih.gov/pubmed/24620025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiu155
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