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Exploring the Influence of the Protein Environment on Metal-Binding Pharmacophores
[Image: see text] The binding of a series of metal-binding pharmacophores (MBPs) related to the ligand 1-hydroxypyridine-2-(1H)-thione (1,2-HOPTO) in the active site of human carbonic anhydrase II (hCAII) has been investigated. The presence and/or position of a single methyl substituent drastically...
Gorde:
| Egile Nagusiak: | , , , |
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| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
American Chemical
Society
2014
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| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4148168/ https://ncbi.nlm.nih.gov/pubmed/25116076 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm500984b |
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