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Pulsed Electron Paramagnetic Resonance Study of Domain Docking in Neuronal Nitric Oxide Synthase: The Calmodulin and Output State Perspective

[Image: see text] The binding of calmodulin (CaM) to neuronal nitric oxide synthase (nNOS) enables formation of the output state of nNOS for nitric oxide production. Essential to NOS function is the geometry and dynamics of CaM docking to the NOS oxygenase domain, but little is known about these det...

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Detalhes bibliográficos
Main Authors: Astashkin, Andrei V., Chen, Li, Zhou, Xixi, Li, Huiying, Poulos, Thomas L., Liu, Ke Jian, Guillemette, J. Guy, Feng, Changjian
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2014
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4148148/
https://ncbi.nlm.nih.gov/pubmed/25046446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jp503547w
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