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Pulsed EPR Determination of Distance between Heme Iron and FMN Centers in a Human Inducible Nitric Oxide Synthase

Mammalian NOS is a homodimeric flavo-hemoprotein that catalyzes the oxidation of l-arginine to NO. Regulation of NO biosynthesis by NOS is primarily through control of interdomain electron transfer (IET) processes in NOS catalysis. The IET from the FMN to heme domains is essential in the delivery of...

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Detalhes bibliográficos
Main Authors: Astashkin, Andrei V., Elmore, Bradley O., Fan, Weihong, Guillemette, J. Guy, Feng, Changjian
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2931817/
https://ncbi.nlm.nih.gov/pubmed/20695464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja104461p
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