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Pulsed EPR Determination of Distance between Heme Iron and FMN Centers in a Human Inducible Nitric Oxide Synthase

Mammalian NOS is a homodimeric flavo-hemoprotein that catalyzes the oxidation of l-arginine to NO. Regulation of NO biosynthesis by NOS is primarily through control of interdomain electron transfer (IET) processes in NOS catalysis. The IET from the FMN to heme domains is essential in the delivery of...

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Autori principali: Astashkin, Andrei V., Elmore, Bradley O., Fan, Weihong, Guillemette, J. Guy, Feng, Changjian
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2931817/
https://ncbi.nlm.nih.gov/pubmed/20695464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja104461p
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