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Role of an Isoform-Specific Serine Residue in FMN-Heme Electron Transfer in Inducible Nitric Oxide Synthase
In the crystal structure of a calmodulin (CaM) bound FMN domain of human inducible nitric oxide synthase (iNOS), the CaM-binding region together with CaM forms a hinge, and pivots on a R536(NOS)/E47(CaM) pair [Xia et al. (2009) J. Biol. Chem. 284, 30708–30717]. Notably, isoform-specific human iNOS S...
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| Auteurs principaux: | , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2012
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3526944/ https://ncbi.nlm.nih.gov/pubmed/22407542 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00775-012-0887-y |
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